Gupta, Babita Kohli, Santvana Farooque, Kamran Jalwal, Gopal Gupta, Deepak Sinha, Sumit Chandralekha Topical airway anesthesia for awake fiberoptic intubation: Comparison between airway nerve blocks and nebulized lignocaine by ultrasonic nebulizer One percent lignocaine in flexible bronchoscopy is as efficacious as 2% lignocaine when administered using the spray as you go technique without concurrent lignocaine nebulization, at a significantly lower total dose of lignocaine administered. Minor complications occurred in 2 patients in each group. (10% in 1% lignocaine group and 6% in 2% lignocaine group P=0.13). Patients receiving sedation were comparable between the 2 groups. Operator-rated overall procedural satisfaction, VAS (72.05Â☒0.16 and 72.20Â☒1.96 in 1% and 2% group respectively P=0.93) and operator-rated cough, VAS were similar between the 2 groups. Baseline characteristics were comparable. A total of 500 patients (250 in each group) were randomized. Secondary objectives were total lignocaine dose administered, patient-rated pain on faces pain scale, cumulative dose of lignocaine and procedural complications. Primary outcomes were operator-rated overall procedural satisfaction, visual analogue scale (VAS)-rated and operator-rated cough, VAS. Nebulized lignocaine was not administered. All received 10% lignocaine spray to the oropharynx along with nasal 2% lignocaine gel. Consecutive patients undergoing bronchoscopy were randomized to receive either 1% or 2% lignocaine solution by spray-as-you-go technique. In this randomized, double blind study, we compared 1% versus 2% lignocaine for topical anesthesia. The ideal concentration of lignocaine for topical anesthesia in bronchoscopy remains investigational. Madan, Karan Biswal, Shiba K Mittal, Saurabh Hadda, Vijay Mohan, Anant Khilnani, Gopi C Pandey, Ravindra M Guleria, Randeep We report a case of primary vaginismus with associated pain that benefited from topical application of lignocaine gel along with systematic desensitization resulting in successful consummation, and suggest that it may be a useful adjunct during finger dilatation in the treatment of vaginismus, specifically in patients who have associated pain or areas of hyperesthesia in the introitus.ġ% Versus 2% Lignocaine for Airway Anesthesia in Flexible Bronchoscopy Without Lignocaine Nebulization (LIFE): A Randomized Controlled Trial. In many cases associated pain or fear of pain may contribute to the maintenance of vaginismus. Vaginismus is a sexual dysfunction in which spasm of vaginal musculature precludes penetrative intercourse. Topical lignocaine for vaginismus: a case report.